ISAAC: AN IMPROVED STRUCTURAL ANNOTATION OF ATTC AND AN INITIAL APPLICATION THEREOF

dc.contributor.advisor	Dushoff, Jonathan	en_US
dc.contributor.advisor	Brian Golding, Paul Higgs	en_US
dc.contributor.author	Szamosi, Judith C.	en_US
dc.contributor.department	Biology	en_US
dc.date.accessioned	2014-06-18T17:00:09Z
dc.date.available	2014-06-18T17:00:09Z
dc.date.created	2012-09-25	en_US
dc.date.issued	2012-10	en_US
dc.description.abstract	<p>We introduce new software (ISAAC: Improved Structural Annotation of attC) to annotate cassette arrays in bacterial integrons by ﬁnding attI and attC sites, and to provide detailed annotation of the attC sites for analysis. We demonstrate an initial application of ISAAC by annotating the cassette complements of all the integrons we identiﬁed in the RefSeq bacterial genome database, and providing an analysis of the patterns of nucleotide frequencies at the structurally important positions in the attCs we’ve found.</p>	en_US
dc.description.degree	Master of Science (MSc)	en_US
dc.identifier.other	opendissertations/7477	en_US
dc.identifier.other	8532	en_US
dc.identifier.other	3349158	en_US
dc.identifier.uri	http://hdl.handle.net/11375/12605
dc.subject	bioinformatics	en_US
dc.subject	genetics	en_US
dc.subject	genomics	en_US
dc.subject	computational biology	en_US
dc.subject	bacteria	en_US
dc.subject	horizontal gene transfer	en_US
dc.subject	Bioinformatics	en_US
dc.subject	Bioinformatics	en_US
dc.title	ISAAC: AN IMPROVED STRUCTURAL ANNOTATION OF ATTC AND AN INITIAL APPLICATION THEREOF	en_US
dc.type	thesis	en_US

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