"Sometime We Stir Up a Hornet's Nest" Practitioners and Paradigms of Genetic Counselling See

The central investigative concern of this thesis is the culture of genetic counselling in Canada--a specialized health service providing information and assistance to families at risk from genetic disorders. In particular, this stu...

An Accelerator Based In Vivo Measurement of Aluminum in Human Bone by Neutron Activation Analysis See

Aluminum is a neurotoxin and has been recognized as a causative agent for dialysis encephalopathy and renal osteodystrophy, as well as possibly being related to Alzheimer's disease. General public exposures to aluminum have incr...

Dopamine Metabolism Quantified in the Human Brain: Tracer Kinetic Analysis of Positron Tomographic Studies See

Mathematical models are used to estimate physiological parameters which are otherwise inaccessible to measurement. When applied to tracer kinetic data obtained in positron tomographic studies, these methods allow for the quantitative analysis...

Application of Spectral Decomposition Analysis to In Vivo Quantification of Aluminum See

Aluminum is a non-essential trace element that accumulates in human bone tissue (Nayak, 2002). Its toxic effects are cumulative and result in painful forms of renal osteodystrophy, most notably a dynamic bone disease and osteom...