Human HtrA2 delays the aggregation of the Alzheimer's disease associated amyloid β-(1-42) peptide See

<p> Human HtrA2 is part of the HtrA family of ATP-independent serine proteases that are conserved in both prokaryotes and eukaryotes and localizes to the inter-membrane space of the mitochondria. Several recent reports&...

Development of a Stereoselective Method for the Synthesis of β-Lactones See

<p> β-Lactones are present in a number of biologically interesting natural products. They also have inherent reactivity due to their strained ring system and act as important synthetic intermediates. In this current wor...

Investigation of the BldB Homologues of Streptomyces Coelicolor: Regulators of Development and Antibiotic Production See

<p> The Streptomyces are invaluable as a natural source of antibiotics and other bioactive compounds used in medicine and agriculture. S. coelicolor is the model streptomycete, and is studied for its complex secondary metaboli...

Structure and Function of B. subtilis MutL See

<p> Maintaining genomic integrity is important for any organism. DNA mismatch repair (MMR) serves to correct errors that occur during DNA replication and recombination, such as unpaired bases or mismatched bases. Mutl i...