Welcome to the upgraded MacSphere! We're putting the finishing touches on it; if you notice anything amiss, email macsphere@mcmaster.ca

Temporal Dynamics and Evolution of SARS-CoV-2 Demonstrate the Necessity of Ongoing Viral Genome Sequencing in Ontario, Canada

dc.contributor.authorSjaarda CP
dc.contributor.authorGuthrie JL
dc.contributor.authorMubareka S
dc.contributor.authorSimpson JT
dc.contributor.authorHamelin B
dc.contributor.authorWong H
dc.contributor.authorMortimer L
dc.contributor.authorSlinger R
dc.contributor.authorMcArthur AG
dc.contributor.authorDesjardins M
dc.contributor.authorMcGeer A
dc.contributor.authorMazzulli T
dc.contributor.authorDouchant K
dc.contributor.authorBrabant-Kirwan D
dc.contributor.authorFattouh R
dc.contributor.authorCampigotto A
dc.contributor.authorPatel SN
dc.contributor.authorFittipaldi N
dc.contributor.authorColautti RI
dc.contributor.authorSheth PM
dc.date.accessioned2021-06-15T15:39:04Z
dc.date.available2021-06-15T15:39:04Z
dc.date.issued2021-05-05
dc.date.updated2021-06-15T15:39:03Z
dc.description.abstract<jats:p>Genome-wide variation in SARS-CoV-2 reveals evolution and transmission dynamics which are critical considerations for disease control and prevention decisions. Here, we review estimates of the genome-wide viral mutation rates, summarize current COVID-19 case load in the province of Ontario, Canada (5 January 2021), and analyze published SARS-CoV-2 genomes from Ontario (collected prior to 24 November 2020) to test for more infectious genetic variants or lineages.</jats:p>
dc.identifier.doihttps://doi.org/10.1128/msphere.00011-21
dc.identifier.issn2379-5042
dc.identifier.issn2379-5042
dc.identifier.urihttp://hdl.handle.net/11375/26587
dc.publisherAmerican Society for Microbiology
dc.rightsAttribution - CC BY This Creative Commons license lets others distribute, remix, tweak, and build upon your work, even commercially, as long as they credit you for the original creation. Recommended for maximum dissemination and use of licensed materials.
dc.rights.licenseAttribution - CC BY
dc.rights.uri2
dc.subjectCOVID-19
dc.subjectG614D
dc.subjectPANGOLIN lineage
dc.subjectSARS-CoV-2
dc.subjectepidemiology
dc.subjectgenetics
dc.subjectinfectious disease
dc.subjectpublic health
dc.subjectBase Sequence
dc.subjectCOVID-19
dc.subjectGenetic Variation
dc.subjectGenome, Viral
dc.subjectHumans
dc.subjectMutation Rate
dc.subjectOntario
dc.subjectPhylogeny
dc.subjectSARS-CoV-2
dc.subjectSequence Analysis, RNA
dc.subjectSpike Glycoprotein, Coronavirus
dc.titleTemporal Dynamics and Evolution of SARS-CoV-2 Demonstrate the Necessity of Ongoing Viral Genome Sequencing in Ontario, Canada
dc.typeArticle

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Temporal Dynamics and Evolution of SARS-CoV-2 Demonstrate the Necessity of Ongoing Viral Genome Sequencing in Ontario, Canad.pdf
Size:
937.94 KB
Format:
Adobe Portable Document Format
Description:
Published version