Welcome to the upgraded MacSphere! We're putting the finishing touches on it; if you notice anything amiss, email macsphere@mcmaster.ca

Temporal Dynamics and Evolution of SARS-CoV-2 Demonstrate the Necessity of Ongoing Viral Genome Sequencing in Ontario, Canada

Files

Temporal Dynamics and Evolution of SARS-CoV-2 Demonstrate the Necessity of Ongoing Viral Genome Sequencing in Ontario, Canad.pdf (937.94 KB)

Date

Authors

Publisher

American Society for Microbiology

Abstract

Genome-wide variation in SARS-CoV-2 reveals evolution and transmission dynamics which are critical considerations for disease control and prevention decisions. Here, we review estimates of the genome-wide viral mutation rates, summarize current COVID-19 case load in the province of Ontario, Canada (5 January 2021), and analyze published SARS-CoV-2 genomes from Ontario (collected prior to 24 November 2020) to test for more infectious genetic variants or lineages.

Keywords

COVID-19, G614D, PANGOLIN lineage, SARS-CoV-2, epidemiology, genetics, infectious disease, public health, Base Sequence, COVID-19, Genetic Variation, Genome, Viral, Humans, Mutation Rate, Ontario, Phylogeny, SARS-CoV-2, Sequence Analysis, RNA, Spike Glycoprotein, Coronavirus

URI

http://hdl.handle.net/11375/26587

Collections

Faculty Publications (via McMaster Experts)

Creative Commons license

Attribution - CC BY
This Creative Commons license lets others distribute, remix, tweak, and build upon your work, even commercially, as long as they credit you for the original creation. Recommended for maximum dissemination and use of licensed materials.

Except where otherwised noted, this item's license is described as Attribution - CC BY This Creative Commons license lets others distribute, remix, tweak, and build upon your work, even commercially, as long as they credit you for the original creation. Recommended for maximum dissemination and use of licensed materials.