Please use this identifier to cite or link to this item:
http://hdl.handle.net/11375/11478
Title: | Highly variable mitochondrial inheritance in intra- and inter-lineage crosses of Cryptococcus gattii |
Authors: | Wilson, Amanda J. |
Advisor: | Xu, Jianping Golding, Brian Golding, Brian |
Department: | Biology |
Keywords: | Biology;Genetics;Other Microbiology;Biology |
Publication Date: | Oct-2011 |
Abstract: | <p>The inheritance of mitochondria and their genomes is predominantly uniparental in plants and animals. However, in fungi, the patterns of inheritance can become complex. Interestingly, in <em>Cryptococcus neoformans</em>, the inheritance pattern is predominantly uniparental. Similar to <em>C. neoformans</em>, closely related <em>Cryptococcus gattii </em>is also a pathogenic fungus, except that it is capable of infecting healthy individuals. In this research, PCR-RFLP was employed on progeny of 14 crosses in order to determine if the mtDNA inheritance pattern is the same in <em>Cryptococcus gattii</em> as was found in <em>C. neoformans.</em> Additionally, the effect of genetic distance between mating partners on mitochondrial inheritance was investigated by using a range of strains across three of the four distinct lineages in <em>C. gattii</em>. My results identified highly variable patterns of inheritance among strains and strain combinations, both within and between the analyzed lineages in <em>C. gattii</em>.</p> |
URI: | http://hdl.handle.net/11375/11478 |
Identifier: | opendissertations/6441 7309 2259341 |
Appears in Collections: | Open Access Dissertations and Theses |
Files in This Item:
File | Size | Format | |
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fulltext.pdf | 1.03 MB | Adobe PDF | View/Open |
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