Gene Expression Regulation Evolution following Whole Genome Duplication: two comparative studies in Xenopus clawed frogs

Abstract

<p> Gene expression, and its mechanisms of regulation, remains a major area for contemporary research in evolution. With its role connecting specific gene sequences and their protein products, contributing to efforts toward understanding the specific contributions of different mechanisms of gene expression regulation is the goal of this thesis. Through two specific case studies, this thesis examines expression regulatory divergence in two different physiological contexts; the immuno-response rag1 and rag2 genes, and the male upregulated sex differentiation gene dmrt1. </p>