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Drug-induced QT interval prolongation and major adverse cardiac events: Meta-analysis of randomized controlled trials

dc.contributor.authorGarcia, M
dc.contributor.authorTsang, J
dc.contributor.authorLohit, S
dc.contributor.authorDeng, F
dc.contributor.authorChang, O
dc.contributor.authorCairns, K
dc.contributor.authorRehman, N
dc.contributor.authorHijazi, W
dc.contributor.authorMbuagbaw, L
dc.contributor.authorHolbrook, AM
dc.contributor.departmentMedicineen_US
dc.date.accessioned2023-10-17T14:05:35Z
dc.date.available2023-10-17T14:05:35Z
dc.date.issued2023-10
dc.description.abstractBackground: QT-prolonging medications (QTPMeds) have become a major source of clinical concern regarding medication-related major adverse cardiac events (MACE); MACE events are rare and it is not clear if all QTPMeds create harm, or in which circumstances. Objectives: Systematically review the study data on the association between QTPMedsand MACE; here we report on a subset of randomized trials. Discussion: Most trials are not statistically powered to detect MACEen_US
dc.identifier.urihttp://hdl.handle.net/11375/29078
dc.language.isoenen_US
dc.subjectQT-prolonging medicationsen_US
dc.subjectmedication-related major adverse cardiac eventsen_US
dc.subjectsystematic reviewen_US
dc.titleDrug-induced QT interval prolongation and major adverse cardiac events: Meta-analysis of randomized controlled trialsen_US
dc.typePosteren_US

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