Studies on a RNA Polymerase Induced in L-Cells Infected with Vesicular Stomatitis Virus

Abstract

<p>A RNA dependent RNA polymerase induced in L-cells infected with VSV was studied. The in vitro properties of this enzyme and the nature of its synthesized products were examined. The products were characterized in terms of size, poly A content, and homology of both the infectious and defective particles of VSV. Analysis of this enzymatic activity during interference indicated a direct correlation between the in vitro activity and the in vivo interference.</p>