Total Synthesis of Methyl O-Methyl-11-Desoxycarnosate
| dc.contributor.advisor | Bell, R. A. | |
| dc.contributor.author | Oommen, Puthenpurackal Kurian | |
| dc.contributor.department | Chemistry | en_US |
| dc.date.accessioned | 2016-07-07T14:42:52Z | |
| dc.date.available | 2016-07-07T14:42:52Z | |
| dc.date.issued | 1968-09 | |
| dc.description.abstract | <p> Synthetic methods for the preparation of 2,7-dimethoxy-1-naphthoic acid are presented. The selective reduction of this acid with sodium in liquid ammonia to give 1,4-dihydronaphthoic acid is described.</p> <p> The selective Birch reduction of 2,7-dimethoxynaphthalene to 1,4-dihydro-2,7-dimethoxynaphthalene has been accomplished. 2,7-Dimethoxy-3- isopropylnaphthalene was converted to 3-keto-12-methoxy-10-carbomethoxy-13-isopropylperhydrophenanthra-4,8,11,13-tetraene via, 1,2,3,4-tertrahydro-7-methoxy-6-isopropyl-1-carbomethoxynaphthalen-2-one. The transformation of 3-keto-12-methoxy-10-carbomethoxy-13-isopropylperhydrophenanthra-4,8,11,13- tetraene to methyl O-methyl-11-desoxycarnosate via methylation, thioketalisation, desulphurisation and hydrogenation is also described.</p> | en_US |
| dc.description.degree | Doctor of Philosophy (PhD) | en_US |
| dc.description.degreetype | Thesis | en_US |
| dc.identifier.uri | http://hdl.handle.net/11375/19761 | |
| dc.language.iso | en_US | en_US |
| dc.subject | synthesis, methyl, desoxycarnosate, acid, hydrogenation | en_US |
| dc.title | Total Synthesis of Methyl O-Methyl-11-Desoxycarnosate | en_US |
| dc.type | Thesis | en_US |