Fluorescently Labeled Sodium Hyaluronate: Synthesis, Characterization and Solution Properties

Abstract

<p> Fluorescence spectroscopy has been proven to be a useful technique for the investigation of the structural, physical and solution properties of polymers. A polymer system containing a photo physical probe can be investigated using fluorescence quenching and polarization. We have randomly labeled sodium hyaluronate (HA) chains with fluorescent dyes such as 1-(1-pyrenyl)methyl amine and N-ε-dansyl-L-lysine, and studied their physical, structural and solution properties, including interactions with surfactants using the above fluorescence techniques.</p>