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Effect of ATP and Alkaline Phosphate on Erythrocyte Deformability

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<p>The effect of altered spectrin phosphorylation on the deformability properties of human erythrocyte membranes was studied using the nucleopore filter method. The shear modulus of elasticity was found to decrease and increase as a result of the incorporation of ATP or alkaline phosphatase, respectively. Purified spectrin was used to immunize rabbits, in order to obtain anti-spectrin antibodies for future experiments.</p>

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Title: Effect of ATP and Alkaline Phosphate on Erythrocyte Deformability, Author: Marianne Vanderwel, Location: Thode

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