Replication and Transcription of Adenovirus Type 2 After Ultraviolet Irradiation

Abstract

<p>When adenovirus type 2 is irradiated with ultraviolet light before infection of KB cells, a significant reduction of virus yields is observed. The ability of the irradiated viral DNA as template for DNA and RNA synthesis was examined. Special emphasis was placed on quantitative determinations of viral DNA and both quantitative and qualitative analysis of viral RNA in infected cells.</p>