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http://hdl.handle.net/11375/23738
Title: | Equivalent Hypertrophy and Strength Gains in HMB or Leucine Supplemented Men |
Authors: | Jakubowski, Josie |
Advisor: | Stuart, Phillips |
Department: | Kinesiology |
Keywords: | HMB;Leucine |
Publication Date: | 2018 |
Abstract: | Ingestion of proteins with high leucine content during resistance training (RT) can augment hypertrophy. There are data suggesting that a leucine metabolite, β-hydroxy, β-methylbutyrate (HMB), may, however, be substantially more anabolic than leucine. Purpose: We aimed to test whether supplementation with HMB versus leucine, added to whey protein, would result in different muscle hypertrophy and strength gains in young men performing resistance training (RT). Methods: Twenty-six resistance-trained men (23 ± 2 y) performed 12 wk of RT with 3 phases. Phase 1: 8 wk of periodized RT (3 training sessions/wk). Phase 2: 2 wk overreaching period (5 sessions/wk). Phase 3: 2 wk taper (3 sessions/wk). Participants were randomly assigned to twice daily ingestion of: whey protein (25 g) plus HMB (1.5 g) (Whey+HMB; n=13) or whey protein (25 g) plus leucine (1.5 g) (Whey+Leu; n=13). Skeletal muscle biopsies were performed before and after RT. Measures of fat and bone-free mass (FBFM), vastus lateralis (VL) muscle thickness and muscle cross-sectional area (CSA – both by ultrasound), muscle fiber CSA, and 1-repetition maximum (1-RM) strength tests were determined. Results: We observed increases in FBFM, VL muscle thickness, muscle CSA and fiber type CSA and 1-RM strength, with no differences between HMB and leucine at any phase. Furthermore, no differences were observed in hormone concentrations between groups, or in time-by-group interactions in hormone concentrations at any phase of the RT program. Conclusion: HMB did not result in greater increases in any measure of muscle mass, strength, or hormonal concentration compared to leucine during 12 weeks of RT. |
URI: | http://hdl.handle.net/11375/23738 |
Appears in Collections: | Open Access Dissertations and Theses |
Files in This Item:
File | Description | Size | Format | |
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Jakubowski_Josie_S_2018-08_MSc.pdf | 6.63 MB | Adobe PDF | View/Open |
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