Please use this identifier to cite or link to this item:
http://hdl.handle.net/11375/19859
Title: | Podocarpic Acid in Diterpene Synthesis |
Authors: | Osakwe, Ejiofor |
Advisor: | Bell, R. A. |
Department: | Chemistry |
Keywords: | Podocarpic Acid;Diterpene Synthesis;kaurane skeleton;chemistry |
Publication Date: | May-1969 |
Abstract: | <p> The C-B-A ring formation sequence has been adopted towards a total synthesis of podocarpic acid starting from 2, 7-dihydroxynaphthalene. Experimental procedures which were developed by other workers have been modified to improve the yields and the purity of the products. </p> <p> Using naturally occurring podocarpic acid, a reliable procedure has been explored for the functionalization of C-6 and C-7 positions in order to construct the 19,6-lactone ring in synthetically satisfactory yields. Catalytic reduction of the aromatic ring C, after functionalization of ring B, has been investigated with the aim of developing a pathway towards the elaboration of the C, D ring system of the kaurane skeleton. </p> |
URI: | http://hdl.handle.net/11375/19859 |
Appears in Collections: | Open Access Dissertations and Theses |
Files in This Item:
File | Description | Size | Format | |
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Osakwe_Ejiofor_N_C_1969May_Phd.pdf | 4.4 MB | Adobe PDF | View/Open |
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