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http://hdl.handle.net/11375/17727
Title: | Some Aspects of the Chemistry of Hydrazides and Thiohydrazides |
Authors: | Elliot, Arthur |
Advisor: | Gibson, M. S. |
Department: | Chemistry |
Keywords: | conversion, hydrazides, heterocyclic ring systemsthiohydrazides, hydrazidic hallides, nucleophilic oxygen, sulfur atom, alpha halogen, oxygen, base, nitrogen, N-aryl ring, benzoxadiazines, benzothiadiazines, heterocyclic |
Publication Date: | May-1971 |
Abstract: | <p> In or der to study the mechanism of their conversio~ into hydrazides and thiohydrazides, a number of hydrazidic halides were treated with compounds containing a nucleophilic oxygen or sulfur atom. </p> <p> The initial products of these reactions were formed from the displacement of the (alpha)-halogen atom of the hydrazidic halide. In cases where there was sufficient activation the group attached to oxygen or sulfur was transferred to nitrogen in the presence of base. </p> <p> Some hydrazides and thiohydrazides containing displace-able groups in the 2-position of an N-aryl ring yielded benzoxadiazines and benzothiadiazines respectively under basic conditions. The reactions exhibited the characteristics of bimolecular nμcleophilic aromatic substitutions. The synthesis of four novel heterocyclic ring systems is described. </p> |
URI: | http://hdl.handle.net/11375/17727 |
Appears in Collections: | Open Access Dissertations and Theses |
Files in This Item:
File | Description | Size | Format | |
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Elliott_Arthur_John_1971May_Ph D.pdf | 46.7 MB | Adobe PDF | View/Open |
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