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http://hdl.handle.net/11375/10561
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DC Field | Value | Language |
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dc.contributor.advisor | MacLean, D.B. | en_US |
dc.contributor.author | Marshall, William D. | en_US |
dc.date.accessioned | 2014-06-18T16:51:52Z | - |
dc.date.available | 2014-06-18T16:51:52Z | - |
dc.date.created | 2009-08-05 | en_US |
dc.date.issued | 1973-08 | en_US |
dc.identifier.other | opendissertations/56 | en_US |
dc.identifier.other | 1559 | en_US |
dc.identifier.other | 924746 | en_US |
dc.identifier.uri | http://hdl.handle.net/11375/10561 | - |
dc.description.abstract | <p>An investigation of the biosynthesis of lycopodine, the major alkaloid of Lycopodium tristachyum, has revealed that L-lysine, but not D-lysine is incorporated into this alkaloid. D-lysine serves as a precursor to pipecolic acid in this species. Sodium malonate has been demonstrated to be a specific precursor to lycopodine, but attempts to verify the postulated intermediacy of piperidineacetic acid. In the elaboration of this alkaloid were unsuccessful.</p> <p>As a means of studying the postulated conversion of lycopodine to annotinine, the major alkaloid of Lycopodium annotinum, specifically labelled 9-14C-lycopodine was synthesized. However the specific incorporation into annotinine of several precursors known to be incorporated into lycopodine could not be demonstrated.</p> | en_US |
dc.subject | Chemistry | en_US |
dc.subject | Chemistry | en_US |
dc.title | Biosynthesis of Lycopodium Alkaloids | en_US |
dc.type | thesis | en_US |
dc.contributor.department | Chemistry | en_US |
dc.description.degree | Doctor of Philosophy (PhD) | en_US |
Appears in Collections: | Open Access Dissertations and Theses |
Files in This Item:
File | Size | Format | |
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fulltext.pdf | 4.57 MB | Adobe PDF | View/Open |
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