Mobile Machine Learning for Real-time Predictive Monitoring of Cardiovascular Disease

Abstract

Chronic cardiovascular disease (CVD) is increasingly becoming a burden for global healthcare systems. This burden can be attributed in part to traditional methods of managing CVD in an aging population that involves periodic meetings between the patient and their healthcare provider. There is growing interest in developing continuous monitoring systems to assist in the management of CVD. Monitoring systems can utilize advances in wearable devices and health records, which provides minimally invasive methods to monitor a patient’s health. Despite these advances, the algorithms deployed to automatically analyze the wearable sensor and health data is considered too computationally expensive to run on the mobile device. Instead, current mobile devices continuously transmit the collected data to a server for analysis at great computational and data transmission expense. In this thesis a novel mobile system designed for monitoring CVD is presented. Unlike existing systems, the proposed system allows for the continuous monitoring of physiological sensors, data from a patient’s health record and analysis of the data directly on the mobile device using machine learning algorithms (MLA) to predict an individual’s CVD severity level. The system successfully demonstrated that a mobile device can act as a complete monitoring system without requiring constant communication with a server. A comparative analysis between the support vector machine (SVM) and multilayer perceptron (MLP) to explore the effectiveness of each algorithm for monitoring CVD is also discussed. Both models were able to classify CVD risk with the SVM achieving the highest accuracy (63%) and specificity (76%). Finally, unlike current systems the resource requirements for each component in the system was evaluated. The MLP was found to be more efficient when running on the mobile device compared to the SVM. The results of thesis also show that the MLAs complexity was not a barrier to deployment on a mobile device.