Chemical Investigations Relating to the Field of Platinum Anticancer Drug Research

Brown, Elaine Brenda

Please use this identifier to cite or link to this item: http://hdl.handle.net/11375/6716

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DC Field	Value	Language
dc.contributor.advisor	Lock, C.J.L.	en_US
dc.contributor.author	Brown, Elaine Brenda	en_US
dc.date.accessioned	2014-06-18T16:36:38Z	-
dc.date.available	2014-06-18T16:36:38Z	-
dc.date.created	2010-06-04	en_US
dc.date.issued	1988-10	en_US
dc.identifier.other	opendissertations/2024	en_US
dc.identifier.other	2876	en_US
dc.identifier.other	1343989	en_US
dc.identifier.uri	http://hdl.handle.net/11375/6716	-
dc.description.abstract	<p>Research relating to platinum anticancer drugs follows two schools of thought. One school strives to unravel the mystery surrounding the mechanism of action of these drugs and the second concentrates on developing new platinum drugs superior to those currently available. The work to be discussed relates to both approaches.</p> <p>The chemistry and structural features of model diammine-dinucleobaseplatinum(II) complexes will be examined and predictions made as to the effects such lesions may have on DNA. In addition, the synthesis and chemicaI characterizations of new pIatinum complexes will be discussed and when possibIe predictions made as to their potential as anticancer agents. The importance of complete and reliable chemical characterizations of these species and others relating to this field will be emphasized.</p>	en_US
dc.subject	Chemistry	en_US
dc.subject	Chemistry	en_US
dc.title	Chemical Investigations Relating to the Field of Platinum Anticancer Drug Research	en_US
dc.type	thesis	en_US
dc.contributor.department	Chemistry	en_US
dc.description.degree	Doctor of Philosophy (PhD)	en_US
Appears in Collections:	Open Access Dissertations and Theses

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