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http://hdl.handle.net/11375/6209
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DC Field | Value | Language |
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dc.contributor.advisor | Lock, L. C. J. | en_US |
dc.contributor.author | Franklin, James Kenneth | en_US |
dc.date.accessioned | 2014-06-18T16:34:28Z | - |
dc.date.available | 2014-06-18T16:34:28Z | - |
dc.date.created | 2010-04-05 | en_US |
dc.date.issued | 1982-11 | en_US |
dc.identifier.other | opendissertations/1537 | en_US |
dc.identifier.other | 2156 | en_US |
dc.identifier.other | 1261660 | en_US |
dc.identifier.uri | http://hdl.handle.net/11375/6209 | - |
dc.description.abstract | <p>Interest in technetium chemistry is derived from the fact that it is a recently-discovered element and from the use of technetium-99m as a radioactive label in diagnostic medicine. Compounds related to both sources of interest have been characterized by X-ray crystallography, vibrational spectroscopy and multinuclear nuclear magnet resonance spectroscopy.</p> <p>The crystal structure of a penicillamine complex of technetium consists of an oxotechnetium(V) core bonded to the S, N, and O atoms of one penicillamine moiety and the S and N atoms of a second. Further characterization, including tracer studies with ⁹⁹ᵐTc, indicate that this complex is identical to an hepatobiliary agent erroneously formulated as a technetium(IV) species. The crystal structure of an anionic catechol complex of technetium also contains the oxotechnetium(V) core and suggests that the technetium(IV) formulation for a number of other radio-pharmaceuticals is incorrect. The crystal structure determination of a complex containing the ethylenebis(2-mercaptoacetamide) ligand forms part of a larger program to design, systematically, new scanning agents.</p> <p>Technetium complexes involving cyanide ligands are shown to be similar to their rhenium analogs.</p> <p>Several new technetium(VII) species were synthesized and used to establish ranges for parameters in the nuclear magnetic resonance spectroscopy of ⁹⁹Tc.</p> | en_US |
dc.subject | Chemistry | en_US |
dc.subject | Chemistry | en_US |
dc.title | Aspects of Technetium Chemistry | en_US |
dc.type | thesis | en_US |
dc.contributor.department | Chemistry | en_US |
dc.description.degree | Doctor of Philosophy (PhD) | en_US |
Appears in Collections: | Open Access Dissertations and Theses |
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File | Size | Format | |
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fulltext.pdf | 2.77 MB | Adobe PDF | View/Open |
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