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DC Field | Value | Language |
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dc.contributor.advisor | Jones, N.L. | en_US |
dc.contributor.author | Bruce, Anne Morag | en_US |
dc.date.accessioned | 2014-06-18T16:33:23Z | - |
dc.date.available | 2014-06-18T16:33:23Z | - |
dc.date.created | 2010-05-05 | en_US |
dc.date.issued | 1985-04 | en_US |
dc.identifier.other | opendissertations/1243 | en_US |
dc.identifier.other | 2455 | en_US |
dc.identifier.other | 1299267 | en_US |
dc.identifier.uri | http://hdl.handle.net/11375/5900 | - |
dc.description.abstract | <p>Indirect calorimetry was used to examine energy expenditure at rest and dietary-induced energy expenditure in normal-weight and overweight volunteers, whose daily energy intakes were similar. The influences of exercise, exercise training, and insulin on dietary-induced energy expenditure were also assessed. At rest energy expenditure was 70.3 kcals/hour in the overweight volunteers, 7.4 kcals/ hour greater than in the normal-weight volunteers. Consumption of a mixed meal of nearly 1000 kcals elicited similar increases in energy expenditure in the normal-weight and overweight volunteers of 10.8 kcals/hour and 12.5 kcals/hour respectively. The results refute the suggestion that a deficiency in energy expenditure at rest or in dietary-induced energy expenditure could be responsible for the greater propensity towards obesity in the overweight volunteers.</p> <p>When exercise preceded the meal, the oxygen debt of exercise summated with the dietary-induced energy expenditure in the normal-weight group. The post-prandial response in the overweight group was similar whether or not exercise preceded the meal, even though the metabolic response to exercise alone was not impaired in the overweight group.</p> <p>Six volunteers (four normal-weight and two over-weight) completed an exercise training programme, and increased their fitness level. However, dietary-induced energy expenditure in response to the 1000 kcal meal was similar before and after training.</p> <p>Hyperinsulinaemia in six normal-weight, non-diabetic volunteers did not influence the post-prandial energy response, although the infusion of insulin and glucose itself elicited an obligatory increase in energy expenditure.</p> <p>The work described in the thesis thus suggests that in mildly overweight individuals there is no evidence that reductions in post-prandial energy expenditure account for their excess weight, but that the lack of a further increase in post-prandial energy expenditure following exercise may do so. The results of the thesis indicate that exercise training does not alter post-prandial energy expenditure, and that hyperinsulinaemia does not influence post-prandial energy expenditure.</p> | en_US |
dc.subject | Medical Sciences | en_US |
dc.subject | Medical Sciences | en_US |
dc.title | Dietary-Induced Energy Expenditure: A Human Study | en_US |
dc.type | thesis | en_US |
dc.contributor.department | Medical Sciences | en_US |
dc.description.degree | Doctor of Philosophy (PhD) | en_US |
Appears in Collections: | Open Access Dissertations and Theses |
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File | Size | Format | |
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fulltext.pdf | 5.32 MB | Adobe PDF | View/Open |
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