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http://hdl.handle.net/11375/29078| Title: | Drug-induced QT interval prolongation and major adverse cardiac events: Meta-analysis of randomized controlled trials |
| Authors: | Garcia, M Tsang, J Lohit, S Deng, F Chang, O Cairns, K Rehman, N Hijazi, W Mbuagbaw, L Holbrook, AM |
| Department: | Medicine |
| Keywords: | QT-prolonging medications;medication-related major adverse cardiac events;systematic review |
| Publication Date: | Oct-2023 |
| Abstract: | Background: QT-prolonging medications (QTPMeds) have become a major source of clinical concern regarding medication-related major adverse cardiac events (MACE); MACE events are rare and it is not clear if all QTPMeds create harm, or in which circumstances. Objectives: Systematically review the study data on the association between QTPMedsand MACE; here we report on a subset of randomized trials. Discussion: Most trials are not statistically powered to detect MACE |
| URI: | http://hdl.handle.net/11375/29078 |
| Appears in Collections: | Medicine Publications |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| QTP-MACE SR RCTs poster 8Oct2023.pdf | 467.78 kB | Adobe PDF | View/Open |
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