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Please use this identifier to cite or link to this item: http://hdl.handle.net/11375/28890
Title: Cluster-based Trajectory Analytics for the Sequence of Functional Loss and Recovery among Older Adults using Big Data
Other Titles: Cluster-Based Trajectory Analytics in Medicine
Authors: Khalili, Ghazal
Advisor: Zargoush, Manaf
Huang, Kai
Department: Computational Engineering and Science
Keywords: Trajectory Analytics;Cluster Analytics;Activities of Daily Living;Sequence Analysis;Functional Loss and Recovery
Publication Date: 2023
Abstract: This work presents comprehensive analytics of trajectories of functional loss and recovery using sequence analysis and clustering techniques. The study focuses on a large dataset consisting of assessments of activities of daily living conducted among nursing home residents. The first main part of this research involves converting the assessments into sequences of disability combinations and utilizing graphical tools and various indicators to gain valuable insights into the trajectories of functional disabilities over time. In the second part of the research, a novel clustering approach is introduced that combines Markov models with distance-based techniques. This hybrid methodology results in 13 distinct clusters of trajectories. The clusters are thoroughly examined, and representative sets are carefully selected based on various criteria. This selection process ensures that the chosen sets accurately represent the characteristics of each cluster. The findings of this study have significant implications for healthcare systems, including developing predictive models which can be utilized to forecast the trajectory of individual patients based on their cluster membership. This enables healthcare providers to anticipate disease progression, tailor treatments, and dynamically adjust care plans, resulting in improved patient outcomes and the overall quality of care. Moreover, the information derived from the analytics can aid in optimizing healthcare systems by facilitating resource allocation and cost optimization. The insights gained can also guide policymakers and families in planning appropriate care for patients. This research advances healthcare decision-making and ensures appropriate support.
URI: http://hdl.handle.net/11375/28890
Appears in Collections:Open Access Dissertations and Theses

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