Please use this identifier to cite or link to this item:
http://hdl.handle.net/11375/27649
Title: | Developing a Reporting Item Checklist for Studies on the Prevalence of HIV Drug Resistance: A Mixed Methods Study |
Authors: | Garcia, Michael Cristian |
Advisor: | Dr. Lawrence Mbuagbaw |
Department: | Health Research Methodology |
Keywords: | HIV;drug resistance;reporting guidelines;prevalence;surveillance;reporting checklist |
Publication Date: | 2022 |
Abstract: | Background: HIV drug resistance limits the effectiveness of antiretroviral therapy. Adequate surveillance of HIV drug resistance prevalence is challenged by heterogenous and inadequate data reporting. In this study, we sought to identify a list of reporting items for studies of HIV drug resistance prevalence and an understanding of why these items are important to report. Methods: We used a mixed-methods sequential explanatory design involving authors and users of studies of HIV drug resistance prevalence. In the quantitative phase we conducted a cross-sectional electronic survey (n=51). Survey participants rated various reporting items on whether they are essential to report, producing validity ratios which were used to produce a draft reporting item checklist. In the qualitative phase, two focus group discussions (n=9 in total) discussed this draft item checklist and which of the items should be reported and why. We also conducted a thematic analysis of the group discussions to identify emergent themes regarding items to be considered for the reporting guideline. Results: We identified 38 potential reporting items including participant characteristics, sampling methods, and resistance testing methods. The strongest themes that emerged from the discussions were agreement over the importance of reporting certain items, concerns over the availability and ethics of reporting certain participant data, the importance of interpretability and comparability, and the necessity for reporting guidelines to appreciate context-specific prevalence research. Conclusions: We have identified a list of reporting items for studies of the prevalence of HIV drug resistance along with an explanation of why researchers believe these items are important. The next steps involve further elaborating upon these findings in the reporting guidelines. |
URI: | http://hdl.handle.net/11375/27649 |
Appears in Collections: | Open Access Dissertations and Theses |
Files in This Item:
File | Description | Size | Format | |
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Garcia_Michael_C_finalsubmission2022Jun_HRM.MSc.pdf | 1.26 MB | Adobe PDF | View/Open |
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