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http://hdl.handle.net/11375/26580
Title: | Risk factors for outbreaks of SARS-CoV-2 infection at retirement homes in Ontario, Canada: a population-level cohort study |
Authors: | Costa AP Manis DR Jones A Stall NM Brown KA Boscart V Castellino A Heckman GA Hillmer MP Ma C Pham P Rais S Sinha SK Poss JW |
Keywords: | Aged;COVID-19;Frail Elderly;Homes for the Aged;Humans;Incidence;Nursing Homes;Ontario;Pandemics;Retirement;Retrospective Studies;SARS-CoV-2 |
Publication Date: | 10-May-2021 |
Publisher: | CMA Joule Inc. |
Abstract: | BACKGROUND: The epidemiology of SARS-CoV-2 infection in retirement homes (also known as assisted living facilities) is largely unknown. We examined the association between home-and community-level characteristics and the risk of outbreaks of SARS-CoV-2 infection in retirement homes since the beginning of the first wave of the COVID-19 pandemic. METHODS: We conducted a population-based, retrospective cohort study of licensed retirement homes in Ontario, Canada, from Mar. 1 to Dec. 18, 2020. Our primary outcome was an outbreak of SARS-CoV-2 infection (≥ 1 resident or staff case confirmed by validated nucleic acid amplification assay). We used time-dependent proportional hazards methods to model the associations between retirement home- and community-level characteristics and outbreaks of SARS-CoV-2 infection. RESULTS: Our cohort included all 770 licensed retirement homes in Ontario, which housed 56 491 residents. There were 273 (35.5%) retirement homes with 1 or more outbreaks of SARS-CoV-2 infection, involving 1944 (3.5%) residents and 1101 staff (3.0%). Cases of SARS-CoV-2 infection were distributed unevenly across retirement homes, with 2487 (81.7%) resident and staff cases occurring in 77 (10%) homes. The adjusted hazard of an outbreak of SARS-CoV-2 infection in a retirement home was positively associated with homes that had a large resident capacity, were co-located with a long-term care facility, were part of larger chains, offered many services onsite, saw increases in regional incidence of SARS-CoV-2 infection, and were located in a region with a higher community-level ethnic concentration. INTERPRETATION: Readily identifiable characteristics of retirement homes are independently associated with outbreaks of SARS-CoV-2 infection and can support risk identification and priority for vaccination. |
metadata.dc.rights.license: | Attribution-NonCommercial-NoDerivs - CC BY-NC-ND |
Rights: | Attribution-NonCommercial-NoDerivs - CC BY-NC-ND This license is the most restrictive of the main Creative Commons licenses, only allowing others to download your works and share them with others as long as they credit you, but they can?t change them in any way or use them commercially. |
URI: | http://hdl.handle.net/11375/26580 |
metadata.dc.identifier.doi: | https://doi.org/10.1503/cmaj.202756 |
ISSN: | 0820-3946 1488-2329 |
Appears in Collections: | Faculty Publications (via McMaster Experts) |
Files in This Item:
File | Description | Size | Format | |
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Risk factors for outbreaks of SARS-CoV-2 infection at retirement homes in Ontario, Canada a population-level cohort study.pdf | Published version | 288.95 kB | Adobe PDF | View/Open |
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