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http://hdl.handle.net/11375/26546
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DC Field | Value | Language |
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dc.contributor.author | Bartoszko JJ | - |
dc.contributor.author | Farooqi MAM | - |
dc.contributor.author | Alhazzani W | - |
dc.contributor.author | Loeb M | - |
dc.date.accessioned | 2021-06-09T15:14:38Z | - |
dc.date.available | 2021-06-09T15:14:38Z | - |
dc.date.issued | 2020-07 | - |
dc.identifier.issn | 1750-2640 | - |
dc.identifier.issn | 1750-2659 | - |
dc.identifier.uri | http://hdl.handle.net/11375/26546 | - |
dc.description.abstract | BACKGROUND: Respiratory protective devices are critical in protecting against infection in healthcare workers at high risk of novel 2019 coronavirus disease (COVID-19); however, recommendations are conflicting and epidemiological data on their relative effectiveness against COVID-19 are limited. PURPOSE: To compare medical masks to N95 respirators in preventing laboratory-confirmed viral infection and respiratory illness including coronavirus specifically in healthcare workers. DATA SOURCES: MEDLINE, Embase, and CENTRAL from January 1, 2014, to March 9, 2020. Update of published search conducted from January 1, 1990, to December 9, 2014. STUDY SELECTION: Randomized controlled trials (RCTs) comparing the protective effect of medical masks to N95 respirators in healthcare workers. DATA EXTRACTION: Reviewer pair independently screened, extracted data, and assessed risk of bias and the certainty of the evidence. DATA SYNTHESIS: Four RCTs were meta-analyzed adjusting for clustering. Compared with N95 respirators; the use of medical masks did not increase laboratory-confirmed viral (including coronaviruses) respiratory infection (OR 1.06; 95% CI 0.90-1.25; I2 = 0%; low certainty in the evidence) or clinical respiratory illness (OR 1.49; 95% CI: 0.98-2.28; I2 = 78%; very low certainty in the evidence). Only one trial evaluated coronaviruses separately and found no difference between the two groups (P = .49). LIMITATIONS: Indirectness and imprecision of available evidence. CONCLUSIONS: Low certainty evidence suggests that medical masks and N95 respirators offer similar protection against viral respiratory infection including coronavirus in healthcare workers during non-aerosol-generating care. Preservation of N95 respirators for high-risk, aerosol-generating procedures in this pandemic should be considered when in short supply. | - |
dc.publisher | Wiley | - |
dc.rights.uri | 2 | - |
dc.subject | COVID-19 | - |
dc.subject | N95 respirators | - |
dc.subject | SARS-CoV-2 | - |
dc.subject | coronavirus | - |
dc.subject | masks | - |
dc.subject | meta-analysis | - |
dc.subject | systematic review | - |
dc.subject | COVID-19 | - |
dc.subject | Coronavirus Infections | - |
dc.subject | Health Personnel | - |
dc.subject | Humans | - |
dc.subject | Infection Control | - |
dc.subject | Masks | - |
dc.subject | Occupational Exposure | - |
dc.subject | Pandemics | - |
dc.subject | Pneumonia, Viral | - |
dc.subject | Randomized Controlled Trials as Topic | - |
dc.subject | Respiratory Protective Devices | - |
dc.subject | Respiratory Tract Infections | - |
dc.subject | Ventilators, Mechanical | - |
dc.title | Medical masks vs N95 respirators for preventing COVID‐19 in healthcare workers: A systematic review and meta‐analysis of randomized trials | - |
dc.type | Article | - |
dc.date.updated | 2021-06-09T15:14:36Z | - |
dc.rights.license | Attribution - CC BY | - |
dc.identifier.doi | https://doi.org/10.1111/irv.12745 | - |
Appears in Collections: | Faculty Publications (via McMaster Experts) |
Files in This Item:
File | Description | Size | Format | |
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Medical masks vs N95 respirators for preventing COVID-19 in healthcare workers A systematic review and meta-analysis of rand.pdf | Published version | 819.55 kB | Adobe PDF | View/Open |
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