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|Title:||MULTIMATERIAL MULTILAYER FABRICATION OF MICROFLUIDIC DEVICES|
|Advisor:||Selvaganapathy, P. Ravi|
|Abstract:||Microﬂuidics technology enables miniaturization, integration and automation of chemical and biochemical assays. Compared to conventional analytical tools, a microﬂuidic device requires small volume of samples and performs assays faster making it a suitable candidate for point- of-care diagnostic devices. Various fabrication techniques for microﬂuidic systems have been developed over past three decades to construct microchannels and microﬂuidics components such as valves, pumps and electrodes. However, most of these methods are either expensive and requiring cleanroom environment or limited to use of single or a few materials primarily due to diﬀerences in process conditions of various materials. Therefore, an easy and robust fabrication technique that is able to integrate diﬀerent microﬂuidic components into a single device is highly sought. Xurography as a rapid prototyping tool was introduced over a decade ago for construction of microchannel. Although this technique has signiﬁcant capability to pattern variety of materials, it has not been applied for important microﬂuidic components such as valves and electrodes. In this thesis, combination of xurography with lamination has been developed to integrate microﬂuidic components. Use of commercially available ﬁlm in variety of materials such as thermoplastics, elastomers and metals signiﬁcantly reduces the cost of fabrication. Also, these materials have diﬀerent properties such as insulating, conductive, elastic, hard, soft, hydrophobic and hydrophilic providing unique functionality in microﬂuidic devices. Therefore, various applications such as ﬂuid ﬂow controll by active and passive valves, DNA electrophoresis, electrochemical sensing, electrokinetic mixing and heating are presented.|
|Appears in Collections:||Open Access Dissertations and Theses|
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|Mohammadzadeh_Aliakbar_201910_PhD.pdf||12.32 MB||Adobe PDF||View/Open|
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