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Please use this identifier to cite or link to this item: http://hdl.handle.net/11375/19859
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dc.contributor.advisorBell, R. A.-
dc.contributor.authorOsakwe, Ejiofor-
dc.date.accessioned2016-07-20T15:54:49Z-
dc.date.available2016-07-20T15:54:49Z-
dc.date.issued1969-05-
dc.identifier.urihttp://hdl.handle.net/11375/19859-
dc.description.abstract<p> The C-B-A ring formation sequence has been adopted towards a total synthesis of podocarpic acid starting from 2, 7-dihydroxynaphthalene. Experimental procedures which were developed by other workers have been modified to improve the yields and the purity of the products. </p> <p> Using naturally occurring podocarpic acid, a reliable procedure has been explored for the functionalization of C-6 and C-7 positions in order to construct the 19,6-lactone ring in synthetically satisfactory yields. Catalytic reduction of the aromatic ring C, after functionalization of ring B, has been investigated with the aim of developing a pathway towards the elaboration of the C, D ring system of the kaurane skeleton. </p>en_US
dc.language.isoenen_US
dc.subjectPodocarpic Aciden_US
dc.subjectDiterpene Synthesisen_US
dc.subjectkaurane skeletonen_US
dc.subjectchemistryen_US
dc.titlePodocarpic Acid in Diterpene Synthesisen_US
dc.contributor.departmentChemistryen_US
dc.description.degreetypeThesisen_US
dc.description.degreeDoctor of Philosophy (PhD)en_US
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