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http://hdl.handle.net/11375/18917
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DC Field | Value | Language |
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dc.contributor.author | Kansal, Vinay | - |
dc.contributor.author | Patriciu, Iulia | - |
dc.contributor.author | Kiang, Michael | - |
dc.date.accessioned | 2016-03-07T23:00:20Z | - |
dc.date.available | 2016-03-07T23:00:20Z | - |
dc.date.issued | 2014-06 | - |
dc.identifier.citation | Schizophr Res. 2014 Jun;156(1):122-7. | en_US |
dc.identifier.other | 10.1016/j.schres.2014.03.023 | - |
dc.identifier.uri | http://hdl.handle.net/11375/18917 | - |
dc.description.abstract | Impaired illness insight in schizophrenia is associated with non-adherence and worse outcomes. Schizophrenia patients also exhibit error-monitoring deficits, which have been proposed to cause poor insight. To test this hypothesis, we examined whether schizophrenia patients' deficits in neurophysiological error-monitoring indices, the error-related negativity (ERN) and error positivity (Pe) event-related potential (ERP) amplitudes, are associated with impaired insight. ERPs were recorded in 18 schizophrenia patients and 18 normal comparison participants during a Stroop task. Patients' subnormal ERN and Pe amplitudes did not correlate with insight, suggesting that impaired insight in schizophrenia stems from neurocognitive mechanisms other than deficient error monitoring. | en_US |
dc.description.sponsorship | Canadian Institutes of Health Research (INO-112359) | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.subject | Cognition | en_US |
dc.subject | Electrophysiology | en_US |
dc.subject | Error positivity | en_US |
dc.subject | Error processing | en_US |
dc.subject | Error-related negativity | en_US |
dc.subject | Event-related potentials | en_US |
dc.subject | Illness insight | en_US |
dc.subject | Neurophysiology | en_US |
dc.subject | Schizophrenia | en_US |
dc.title | Illness insight and neurophysiological error-processing deficits in schizophrenia | en_US |
dc.type | Article | en_US |
dc.contributor.department | Medical Sciences (Neuroscience and Behavioral Science) | en_US |
Appears in Collections: | Faculty Publications |
Files in This Item:
File | Description | Size | Format | |
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ern_schizres_rev_031814_openaccess.pdf | article manuscript | 1.01 MB | Adobe PDF | View/Open |
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