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http://hdl.handle.net/11375/17958
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DC Field | Value | Language |
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dc.contributor.advisor | Spenser, I. D. | - |
dc.contributor.author | Hill, Robert Edward | - |
dc.date.accessioned | 2015-08-25T12:39:08Z | - |
dc.date.available | 2015-08-25T12:39:08Z | - |
dc.date.issued | 1970-05 | - |
dc.identifier.uri | http://hdl.handle.net/11375/17958 | - |
dc.description.abstract | The biosynthesis of vitamin B₆ was studied by administering radioactive putative precursors to a mutant of Escherichia coli B., WG2. A new method for the isolation and purification of the vitamin congener, pyridoxol, is described. Partial degradation of the radioactive pyridoxol revealed non-random incorporation of a number of precursors into pyridoxol. On the basis of these results a biosynthetic scheme was constructed which envisages that pyridoxol is derived from three glycerol units. One of these is incorporated via pyruvic acid as a two carbon fragment at the oxidation level of acetaldehyde. The other two are incorporated intact, possibly by way of triose phosphate (Fig. 33). | en_US |
dc.language.iso | en | en_US |
dc.subject | biochemistry | en_US |
dc.subject | biosynthesis | en_US |
dc.subject | vitamin B₆ | en_US |
dc.subject | Escherichia coli B., WG2 | en_US |
dc.title | Biosynthesis of Vitamin B₆ | en_US |
dc.contributor.department | Biochemistry | en_US |
dc.description.degreetype | Thesis | en_US |
dc.description.degree | Doctor of Philosophy (PhD) | en_US |
Appears in Collections: | Open Access Dissertations and Theses |
Files in This Item:
File | Description | Size | Format | |
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Hill_Robert_E_1970May_PhD.pdf | 32.38 MB | Adobe PDF | View/Open |
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