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Please use this identifier to cite or link to this item: http://hdl.handle.net/11375/17958
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DC FieldValueLanguage
dc.contributor.advisorSpenser, I. D.-
dc.contributor.authorHill, Robert Edward-
dc.date.accessioned2015-08-25T12:39:08Z-
dc.date.available2015-08-25T12:39:08Z-
dc.date.issued1970-05-
dc.identifier.urihttp://hdl.handle.net/11375/17958-
dc.description.abstractThe biosynthesis of vitamin B₆ was studied by administering radioactive putative precursors to a mutant of Escherichia coli B., WG2. A new method for the isolation and purification of the vitamin congener, pyridoxol, is described. Partial degradation of the radioactive pyridoxol revealed non-random incorporation of a number of precursors into pyridoxol. On the basis of these results a biosynthetic scheme was constructed which envisages that pyridoxol is derived from three glycerol units. One of these is incorporated via pyruvic acid as a two carbon fragment at the oxidation level of acetaldehyde. The other two are incorporated intact, possibly by way of triose phosphate (Fig. 33).en_US
dc.language.isoenen_US
dc.subjectbiochemistryen_US
dc.subjectbiosynthesisen_US
dc.subjectvitamin B₆en_US
dc.subjectEscherichia coli B., WG2en_US
dc.titleBiosynthesis of Vitamin B₆en_US
dc.contributor.departmentBiochemistryen_US
dc.description.degreetypeThesisen_US
dc.description.degreeDoctor of Philosophy (PhD)en_US
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