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http://hdl.handle.net/11375/15293
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DC Field | Value | Language |
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dc.contributor.advisor | Brennan, John D. | en_US |
dc.contributor.advisor | Capretta, Alfredo | en_US |
dc.contributor.author | Helka, Blake-Joseph | en_US |
dc.date.accessioned | 2014-06-18T21:13:31Z | - |
dc.date.created | 2013-09-25 | en_US |
dc.date.issued | 2013-10 | en_US |
dc.identifier.other | opendissertations/8321 | en_US |
dc.identifier.other | 9451 | en_US |
dc.identifier.other | 4629927 | en_US |
dc.identifier.uri | http://hdl.handle.net/11375/15293 | - |
dc.description.abstract | <p>Fabrication of microarrays using sol-gel immobilization has been utilized as an approach to develop high density biosensors. Microarray fabrication using various printing techniques including pin-printing and piezoelectric ink jet printing methods has been demonstrated. However, only limited characterization to understand the encapsulated biomolecule-material interface has been reported. Herein, Chemical characterization using X-ray photoelectron spectroscopy (XPS) and infrared spectroscopy (IR) on pin-printed microarrays of sol-gel derived acetylcholinesterase (AChE) microarrays is reported. Furthermore, the <em>in situ</em> fabrication of microarrays following the sol-gel process using piezoelectric ink jet printing methods was explored. Through techniques measuring solution viscosity, surface tension and particle size, important aspects of bio-ink formulation for piezoelectric ink jet printing were identified. Combined, a greater understanding towards the fabrication and characterization of sol-gel derived microarrays was achieved through this exploratory research.</p> | en_US |
dc.subject | microarrays | en_US |
dc.subject | sol-gel | en_US |
dc.subject | x-ray photoelectron spectroscopy | en_US |
dc.subject | infrared spectroscopy | en_US |
dc.subject | printing | en_US |
dc.subject | Analytical Chemistry | en_US |
dc.subject | Materials Chemistry | en_US |
dc.subject | Analytical Chemistry | en_US |
dc.title | Surface Characterization and Comparison of Contact vs. Non-Contact Printed Sol-Gel Derived Material Microarrays | en_US |
dc.type | thesis | en_US |
dc.contributor.department | Chemical Biology | en_US |
dc.date.embargo | 2014-09-25 | - |
dc.description.degree | Master of Science (MSc) | en_US |
dc.date.embargoset | 2014-09-25 | en_US |
Appears in Collections: | Open Access Dissertations and Theses |
Files in This Item:
File | Size | Format | |
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fulltext.pdf | 2.2 MB | Adobe PDF | View/Open |
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