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Please use this identifier to cite or link to this item: http://hdl.handle.net/11375/14177
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dc.contributor.advisorFreeman, K.B.en_US
dc.contributor.authorBartoov, Benjaminen_US
dc.date.accessioned2014-06-18T17:06:34Z-
dc.date.available2014-06-18T17:06:34Z-
dc.date.created2014-05-21en_US
dc.date.issued1971-03en_US
dc.identifier.otheropendissertations/9002en_US
dc.identifier.other10091en_US
dc.identifier.other5606408en_US
dc.identifier.urihttp://hdl.handle.net/11375/14177-
dc.description<p>Department title for this thesis is Molecular Biology, which is not listed in the categories.</p>en_US
dc.description.abstract<p>Mitochondria from mammalian cells synthesize protein. To characterize this sytem, high molecular weight RNA and ribosomal components from mitochondria of rat, mouse and human sources were investigated. Novel ribosomal RNA and ribosomal components <strong></strong>were found in these organisms which are unique compared with their counterparts in the cytoplasm or bacteria in respect to their physical properties, chemical composition and conformation. <strong></strong>The RNA sedimentation cofficients of 15 and 13 S, electrophoretic mobilities of about 21 and 12.5 S<sub>E </sub>and 20.5 and 11.0 S<sub>E </sub>for rodent and human cells respectively, and a high A+U content. The mitochondrial ribosomal RNA was transcribed from the mitochondria originated from an autonomous prokaryotic ancestor whic established a symbiotic relationship in the contemporary eukaryotic cell in which the original prokaryotic symbiont lost part of its autonomy.</p>en_US
dc.subjectmammalsen_US
dc.subjectcellsen_US
dc.subjectmitochondriaen_US
dc.subjectraten_US
dc.subjectmouseen_US
dc.subjecthumanen_US
dc.subjectBiochemistry, Biophysics, and Structural Biologyen_US
dc.subjectLife Sciencesen_US
dc.subjectMolecular Biologyen_US
dc.subjectBiochemistry, Biophysics, and Structural Biologyen_US
dc.titleMammalian Mitochondrial Ribonuclcatesen_US
dc.typethesisen_US
dc.contributor.departmentBiologyen_US
dc.description.degreeDoctor of Philosophy (PhD)en_US
Appears in Collections:Open Access Dissertations and Theses

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