Cellular DNA Metabolism After Infection by Adenovirus Type 12

Please use this identifier to cite or link to this item: http://hdl.handle.net/11375/13633

Full metadata record

DC Field	Value	Language
dc.contributor.advisor	Mak, Stanley	en_US
dc.contributor.author	Pater, Mary M.	en_US
dc.date.accessioned	2014-06-18T17:04:41Z	-
dc.date.available	2014-06-18T17:04:41Z	-
dc.date.created	2009-08-21	en_US
dc.date.issued	1975-11	en_US
dc.identifier.other	opendissertations/847	en_US
dc.identifier.other	1751	en_US
dc.identifier.other	961933	en_US
dc.identifier.uri	http://hdl.handle.net/11375/13633	-
dc.description.abstract	<p>The effect of infection by human adenovirus type 12 on the pre-existing cellular DNA was examined in an abortive system as well as a productive system. The results were discussed in relation to the known effects of infection on chromosomes and the mechanism by which such effects are induced.</p> <p>The effects of viral infection on certain aspects of DNA replication in human KB cells were also studied. It was observed that the ligation of the "Okazaki fragments" was slower after infection by this virus. It was also observed that the inhibition of cell DNA synthesis by this virus is not a random process and that certain classes of DNA, as distinguished by their high buoyant density and by their high reiteration frequency, was selectively synthesized.</p>	en_US
dc.subject	Biology	en_US
dc.subject	Biology	en_US
dc.title	Cellular DNA Metabolism After Infection by Adenovirus Type 12	en_US
dc.type	thesis	en_US
dc.contributor.department	Biology	en_US
dc.description.degree	Doctor of Philosophy (PhD)	en_US
Appears in Collections:	Open Access Dissertations and Theses

Files in This Item:

File	Size	Format
fulltext.pdf Open Access	4.32 MB	Adobe PDF	View/Open